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The GSH-induced disintegration of nanoparticles was demonstrated as an example of this system, allowing the release of active platinum metabolites, which covalently bound to the target DNA and induced apoptosis in cancer cells

Those who are severely immunosuppressed can get PML, which can be fatal

A study dedicated to the cachexia effects in a GI cancer cohort revealed that patients who received cysteine supplementation in parenteral nutrition had shorter overall survival as compared to those who did not receive cysteine (167)

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99101 The differential decrease in insulin responsiveness by the two main branches of insulin signalling causes an imbalance in the effects of insulin on the endothelium, leading to the development of a pro-atherogenic profile