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Naunyn Schmiedebergs Arch Pharmacol 394(8):17371755

Injecting on an empty stomach versus after eating does not meaningfully change semaglutide absorption, since it enters the bloodstream through subcutaneous tissue rather than the digestive tract

The transition interval to near saturation corresponds to oxygen partial pressure found in peripheral tissues, facilitating Hb saturation in the lungs as well as oxygen delivery to the tissues