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Tenderness often starts within the first hour as the arm muscle adjusts to the injection, and soreness reaches its peak between 12 and 24 hours according to influenza post-marketing surveillance reports

Because that figure comes from rodent research, many start patients at the low end (about 5 mcg/kg or a flat 250 mcg) and adjust over one to two weeks

250 mcg Other Ingredients: Vegetable Capsule (Hypromellose, Gellan Gum), Microcrystalline Cellulose, Vegetable Stearate, Salcaprozate Sodium

THE HYPOTHALAMIC-PITUITARY-ENDOCRINE AXIS Many of the classic endocrine hormones (e.g., cortisol, thyroid hormone, sex steroids, growth hormone) are regulated by complex reciprocal interactions among the hypothalamus, anterior pituitary, and endocrine glands (Table 381)

You might hear anecdotes from friends or spot clinics offering these injections as an energy booster