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Damage-associated molecular patterns, such as high mobility group box 1 (HMGB1), initiate this phenotypic shift by engaging signaling pathways like toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE), which in turn activate downstream effectors, including nuclear factor kappa-B (NF-B) and the NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome (Tastan and Heneka, 2024

Probiotic supplementation has a limited effect on circulating immune and inflammatory markers in healthy adults: a systematic review of randomized controlled trials

82174450], the Shanghai Clinical Medical Research Center of Traditional Chinese Medicine Oncology/the Science and Technology Commission of Shanghai Municipality (STCSM) [no

Indeed, every organ of the body maintains its own GSH concentrations based on their metabolic activity, generation of ROS and cellular needs