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It would be quite interesting to follow these studies with an investigation of brain mitochondria and estrogen receptors to determine whether sex steroid hormones in the brain might be involved in the gender differences seen in the prevalence of depression

Following single oral doses R , S -lipoic acid (racemic mixture), peak plasma concentrations of R -lipoic acid were found to be 40%-50% higher than S -lipoic acid, suggesting a differential absorption in favor of the R -enantiomer (6, 8, 11)

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The 77 Se-NMR resonance of benzisoselenazolones ( 133 observed at 914.33974.90 ppm) and diselenides ( 2534 observed at 443.48447.93 ppm) are in agreement with previously published data 64,65,66