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Conjugation with glutathione receptors renders toxic substances more soluble, and therefore more readily exocytosed from the cell

Deficiency of GSH, the major intracellular thiol, has been shown in human patients with acute pancreatitis, HIV infection, hyperthyroidism, Type I diabetes, and cirrhosis, 3-6 and has been associated with disease severity and decreased survival in some studies

B vitamins, especially the methylated vitamins B6, B9, and B12, are also critical to help the body produce glutathione

The 50 CCl 4 -treated mice were divided into 5 groups: the first 10 mice served as positive (CCl 4- induced liver fibrosis) group

Electrolyte imbalance may also cause fatigue and muscle cramps