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Nicotinamide was highly correlated with serum insulin, HOMA-IR, final body weight, total adipose mass, liver triglyceride, and serum glucose (r = 0.50 to 0.73), while N-acetylserotonin was negatively correlated with all phenotypic parameters except liver malondialdehyde (r = 0.50 to 0.72)

We agree with commenters that comparing autoimmune diseases and cancer as related to immunosuppression is difficult due to several factors such as the location of cancer and the modality of treatment