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B.Behavior (2011)

Oxidative stress caused by iron overload further induces lipid peroxidation, destroys mitochondrial membrane and function, and causes redox imbalance

doi: 10.1021/acs.jmedchem.8b00315 Summary Keywords ferroptosis, lipid metabolism, reactive oxygen species biology, iron homeostasis, immunity, autoimmune diseases Citation Fan J, Jiang T and He D (2023) Emerging insights into the role of ferroptosis in the pathogenesis of autoimmune diseases

Analogs targeting arginase and arginine deiminase, the enzymes involved in arginine depletion, have been developed

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