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An open trial compared L-carnitine (500 mg twice daily) alone to 440 mg L-carnitine plus 250 mg L-arginine, 40 mg zinc, 120 mg vitamin E, 80 mg glutathione, 60 mcg selenium, 15 mg CoQ10, and 800 mcg folic acid per day

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Also, spermidine is capable of conferring immunoregulatory potential in alleviating EAE symptoms through the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme on dendritic cells (116)

Contributing to the regulation of blood sugar levels, growth and repair of muscle and bone, growth hormone production, and wound healing