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Many of the biological properties and effects of cisplatin have been well documented (Rosenberg, 1985

Serotonin decreases cytokines transcription, oxidative stress and APAP-adducts formation in the liver To assess whether cytokines concentrations induced by APAP in the serum are influenced by 5-HT levels, we measured TNF- and IL-6 concentrations in serum 24 hours following APAP administration