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It has been described for roGFP1-iL that the insertion C147CL and the substitution H148S lower the thermodynamic stability of the inter-strand disulfide C147C204 resulting in a less negative E of the sensor (Lohman and Remington, 2008)

12/15-LOX are considered as one of the key regulators of ferroptotic cell death (Yang et al., 2016

In summary, our results suggest that HIF2 transcriptionally upregulates MCJ, which in turn leads to the secretion of legumain

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