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In other neurodegenerative diseasessuch as epilepsy, stroke, and brain traumaa rapid rise in the levels of extracellular glutamic acid can cause severe neuronal damage

Schalock PC, Storrs FJ, Morrison L

doi: 10.1007/s00726-011-0867-5 24 CardosoBRHareDJBushAIRobertsBR

Taking into account the pathogenic mechanisms of ALS, the new therapeutic strategies have as the main goal to activate the metabolic pathways related to the mitochondria, production of energy and increase the antioxidant defense levels