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A 2019 meta-analysis noted mixed outcomes in autoimmune thyroid conditions, with some studies showing reduced TPO antibodies and improved TSH control, while others showed minimal clinical benefit

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Studies have described that flavonols and their derivatives are likely the substrate for GSTLs, which tightly bind to these small molecules ( Arabidopsis and wheat Lambda class GSTs ( AtGSTL1, TaGSTL1 , and TaGSTL3) have been identified to be localized in cytosol, whereas others ( AtGSTL2 and TaGSTL2) are chloroplast localized (Theodoulou et al., 2003)