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Furthermore, a meta-analysis encompassing 13 studies comprising 1,606 females diagnosed with PCOS revealed that sustained administration of metformin leads to a notable decrease in miscarriage and preterm birth rates, alongside an increase in full-term pregnancies

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The combination of increasing import capacity and Zn mobilization can delay the onset of Zn limitation, but ultimately growth ceases in the absence of Zn

The cytotoxic activity of gliotoxin is generally mediated by direct inactivation of essential protein thiols [4] and by inhibition of the respiratory burst in neutrophils by disrupting NADPH oxidase assembly, thereby facilitating in vivo fungal dissemination [5], [6]

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