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Description

Previously, free Ts24GST and bound Ts24GST-GSH systems were analyzed with PropKa algorithm [ 12 ] to assign protonation states of protein ionizable residues considering a pH value of 7.4

Later, GSH-Px levels decreased significantly on the 30th day compared to the 21st day of the recovery period, and these levels are lower than the baseline [25]

Together, these findings suggest a model in which aberrant ubiquitination and/or SUMOylation of GLT-1 following OGD reduces transporter availability and impairs glutamate clearance