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Mechanistically, (+)-CLA prevents Nrf2 ubiquitination and boosts Nrf2 stability by selectively interacting with the cys-151 residue of Keap1 (Wang et al., 2020)

Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis

Nature 1954, 173 (4417), 12231227

Curr Opin Support Palliat Care 3:263268 Adams V, Linke A, Wisloff U, Dring C, Erbs S, Krnkel N, Witt CC, Labeit S, Mller-Werdan U, Schuler G, Hambrecht R (2007) Myocardial expression of Murf-1 and MAFbx after induction of chronic heart failure: effect on myocardial contractility

154 Melatonin Melatonin, a hormone produced in the brain that helps regulate the bodys circadian rhythms, plays a role in normal sperm production and protection against free radical damage, and low melatonin levels have been noted in men with infertility