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The two cysteines in this motif catalyze glutathione (GSH)-dependent thiol-disulfide exchange reactions, i.e., the reduction of protein disulfides and, with high specificity, reversible (de-)glutathionylation [19] Oxidized Grxs are reduced by GSH, the resulting GSH disulfide (GSSG) by glutathione reductase (GR) using NADPH as electron source [20]

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Opioid withdrawal investigations have continued in Russian and European literature

References Bermano G, et al

They act as signaling molecules that tell your body to perform specific functions like producing growth hormone, repairing tissue, or building collagen