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Description

Nature 606 , 10151020 (2022)

Prostate cancer vasculature may express surface prohibitin in configurations similar to adipose vasculature, making it potentially vulnerable to the same targeting approach

Chiu, C

Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R