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Standard treatment approaches include rest, ice, anti-inflammatory medications, physical therapy, bracing, and in some cases cortisone injections

Increased GST and/or GT tumor expression, generally considered as a bad prognosis marker (associated with drug resistance and disease progression), and could potentially be used as a predictive marker, allowing doctors, after biopsy, to identify which patients will respond best to GST or GT-activated prodrugs

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Aquacult Int 4:3141 Tsangaris C, Papathanasiou E, Cotou E (2007) Assessment of the impact of heavy metal pollution from a ferro-nickel smelting plant using biomarkers