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H.et al (1999)

Consistent with this, a recent study demonstrated that catabolism of extracellular glutathione can supply cysteine to support tumor growth under cystine-limited conditions 150

The homogenates were centrifuged at 10,000 g for 10 min at 4 C

Instead, it can be mimicked by agents that induce the unfolded protein response (UPR), a signal transduction pathway activated by the accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) [65]