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Description

Although the DPPH scavenging mechanism of usnic acid has not been fully elucidated, it is believed that phenolic groups can stabilize the radicals formed on the phenolic carbon through their resonance structure

Nature 536 , 354358 (2016)

The chemicals identified as degradation enhancers include inhibitors of cellular signaling pathways such as poly-ADP ribosylation (PARG inhibitor PDD00017273), unfolded protein response (PERK inhibitor GSK2606414), and protein stabilization (HSP90 inhibitor luminespib)