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The compound's development represents years of medicinal chemistry optimization, resulting in a 10-fold improvement in potency over parent compounds while maintaining excellent safety margins in preclinical studies

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Once the needle is injected, it releases liquid into your system, which can cause some pain

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doi:10.1056/NEJM196010132631504 9.RUBIN A, SPRITZ N, MEAD A, HERRMANN R, BRAVEMAN W, LUCKEY E