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While there are several publications on secondary blepharospasm in the context of central nervous system (CNS) lesions, peripherally-induced blepharospasm is relatively rare [ 52 , 53 ]

doi:10.1038/s41586-021-03275-y

That level of integration is what separates a supervised medical protocol from a DIY experiment

Complementary peptides that individuals may consider alongside orforglipron include MOTS-c for mitochondrial metabolism and exercise capacity, AOD-9604 or Fragment 176-191 for additional fat mobilization, NAD+ supplementation for cellular energy and longevity support, and BPC-157 for GI support and tissue healing

Most concluded that the substance appears quite promising, but that there are too many unknowns to justify its clinical use at this time