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Nutrients 12(6):1790

Cell, 2005)

Prominent features of cholestasis, both acute and chronic, are itching and malabsorption of fat and fat-soluble nutrients

Studies have shown that early treatment with resveratrol can significantly reduce hearing thresholds at all frequencies, and can reduce the mRNA expression levels of pro-apoptotic genes Bax and Bak, and increase the mRNA expression level of anti-apoptotic genes Bcl-2 and Bcl-xL, but there was no significant difference in hearing levels between the late treatment group and the control group [114]