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Together, these systems converge in PI3k/AKT/mTOR signaling cascades and functionally interconnect to promote phosphorylation of proteins [10, 14,15,16]

At the metabolomics level, the fatty acid biomarkers identified include capric acid, caproic acid, propionic acid, and heptanoic acid and showed a significant reduction in at least one of the severity groups listed above, compared to the healthy controls and the concentration of the uremic toxins IS and p-CS were significantly high at the advanced stage

Glia 63:328340 Fonnum F, Johnsen A, Hassel B (1997) Use of fluorocitrate and fluoroacetate in the study of brain metabolism

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