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Similarly, peroxidases can also release the hydrophobic cargo of poly (propylene sulfide) nanoparticles in the presence of H 2 O 2 (Allen et al., Remediation of phenol waste water by immobilized HRP in magnetic nanoparticles involves the oxidation of phenols in the presence of H 2 O 2 and the reaction of the phenoxy radicals with each other in a non-enzymatic process forming polymers

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Consequently, PGA formation constitutes an overflow pathway that becomes prominent only when normal glutathione homeostasis is compromised, making it a valuable marker of impaired cellular antioxidant capacity and metabolic stress