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Secondary validation incorporated Philippines FDA cosmetic notification portal records, ASEAN Cosmetics Directive harmonization documentation, Bureau of Philippine Standards testing protocols, and Department of Trade and Industry BIKAS program filings

Shows the highest GLUT4 translocation and IGF-1R sensitivity

Eli Lilly & Company and the National Center for Advancing TranslationalSciences (NCATS), Bethesda, Maryland

Abstract Purpose This review provides an update on the current clinical, epidemiological and pathophysiological evidence alongside the diagnostic, prevention and treatment approach to chemotherapy-induced peripheral neuropathy (CIPN)