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Dysfunctional glucose metabolism in Alzheimer's disease onset and potential pharmacological interventions

High-dose vitamin C therapy for KRAS/BRAF mutant cancers More than 80 years ago, the biochemist Otto Warburg observed that cancer cells consume more glucose and produce more lactate even in the presence of ample oxygen as compared with normal cells

Zhang L, Tao L, Shi T, Zhang F, Sheng X, Cao Y, Zheng S, Wang A, Qian W, Jiang L (2015) Paeonol inhibits B16F10 melanoma metastasis in vitro and in vivo via disrupting proinflammatory cytokines-mediated NF-B and STAT3 pathways