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2023;12(10):e12371doi

Complications BDH1 Protects against Diabetic Cardiomyopathy by Improving Mitochondrial Function and Suppressing Cardiomyocyte Apoptosis Via Activation of the AKT/GSK3 Pathway Yan Wang, Yanan Cheng, Jianbo Wu, Yu Zhao, Di Wang, Longyan Yang, Dong Zhao Received March 26, 2025 Accepted September 8, 2025 Published online January 19, 2026 DOI: [Epub ahead of print] 2,119 View 127 Download Abstract PDFSupplementary MaterialPubReader ePub Background Diabetic cardiomyopathy (DCM) is the main cause of heart failure in diabetes patients with no effective therapies currently available

Lentiviral transduction of mRFP-GFP-LC3 shRNA and autophagic flux determination Lentiviruses encoding short hairpin RNAs (shRNA) to human mRFP-GFP-LC3-puro were constructed by Hanbio Biotechnology (Hanbio, Shanghai, China)