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From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function

While much of the published evidence has been generated through laboratory and animal research, Epithalon continues to serve as an important research tool for exploring the biological mechanisms associated with healthy cellular aging

Colodro-Conde, L

This analysis identified several targets of the transcriptional mediators of hypoxia HIF1 and HIF2 as the most significantly enriched among the genes with increased expression, while targets of Tbr2 and the oncogene Bmi1 were most enriched among the genes with decreased expression, consistent with decreased differentiation (Fig 3D and E)