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They study authors wrote: Neuropsychiatric symptoms are a well-described side effect of systemic corticosteroid therapy and can range from mild to severe. In this case including psychosis

Its the same area where youd get a flu shot

Sargeant TD, Guler MO, Oppenheimer SM et al (2008) Hybrid bone implants: self-assembly of peptide amphiphile nanofibers within porous titanium

Prednisone is commonly used

The low CSF-to-plasma ratio of compound D and the absence of compound Q in CSF may suggest the need for Phase Ib dosing studies to explore novel strategies for increasing Q bioavailability and D levels in the CNS