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reported an LD 50 of 7,727 mg/kg for a 70% ethanol leaf extract of R

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Across multiple population pharmacokinetic (PPK) analyses of antiprogrammed cell death protein-1/ligand-1 (anti-PD-1/PD-L1) therapies, female biological sex is associated with lower clearance (2227% lower than males) after accounting for body size and albumin (Ryman and Meibohm 2017