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Aside from deactivating radicals and reactive oxidants, glutathione participates in thiol protection and redox regulation of cellular thiol proteins under oxidative stress by protein S-glutathionylation, a redox-regulated post-translational thiol modification

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GSK3 inhibits macropinocytosis and lysosomal activity through the Wnt destruction complex machinery

In the present study, direct association between GPx4 and NCOA4 has not been demonstrated in terms of protein expression levels in our mouse experiment (Supplementary Fig