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This manuscript has unrevealed the limitations of existing treatments and approaches

vivax following informed consent and ethical approval

Eliminate or postpone need of surgery

The therapeutic scope of probiotics extends to metabolic health, with oral supplementation of Bifidobacterium breve improving glycemic control in T2DM and Anaerobutyricum soehngenii enhancing intestinal barrier function through SCFA production, improving metabolic indicators in prediabetes ( F.n decolonization, and enhances tryptophan metabolism and secondary bile acid conversion, leading to reduced lipid accumulation, decreased inflammatory reaction, and enhanced tumor inhibition effect, providing a promising approach for treating F.n -positive CRC (Zhou et al., 2025)