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4.1 Acute liver failure ALF is an intractable clinical syndrome with multiple causes featured by a fast reduction in hepatic function, increased aminotransferases, altered mentation, and disturbed coagulation in the absence of chronic liver diseases

Depending on the signal stimulation of the TME, TAMs can polarize into two distinct phenotypes: the classically activated macrophages (M1) under proinflammatory conditions (IFN, TNF, GM-CSF) or the alternatively activated (M2) macrophages through IL-10, TGF, IL-4 and IL-13 (54)

1 and SULTR1

the excretion of solute wastes and the regulation of body fluid volumes

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