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Ion-exchange chromatography Ion-exchange chromatography (IEXC) was introduced to protein separation in the 1960s and plays a major role in the purification of biomolecules [7]

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There is growing evidence that various neurodegenerative diseases, including Parkinsons disease, stroke, Huntingtons disease, and traumatic brain injury, are associated with ferroptosis (98, 99)

These modifications rely on enzymatic activities that use metabolites derived from central carbon metabolism 6 , indicating that metabolism is intertwined with the epigenetic regulation of chromatin states