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Caron P, Grunenwald S, Persani L, Borson-Chazot F, Leroy R, Duntas L

Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR)

"This is a situation in which a patient could become septic very quickly if left untreated." Risk factors for kidney stones Approximately 1 in 10 people will develop kidney stones