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A significant drop in serum ALT and AST indicated better liver integrity and less hepatic leakage

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Application in Studies of Hepatic Metabolic Disorders and Fatty Liver Disease The liver is a central metabolic organ responsible for lipid, glucose, and protein metabolism

Disruption of the glucagon receptor specifically leads to increased VGF levels in cells To further investigate the mechanism underlying cell glucagon hypersecretion following glucagon receptor knockout, we analyzed differentially expressed genes (DEGs) in -cells between the WT and GCGR-KO groups