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The process of scar formation probably exerts a role in protecting the integrity of the blood brain barrier (BBB) and in avoiding further cellular degeneration

The following data were recorded: demographics, diabetes duration, insulin type, and therapeutic scheme daily dose, number of injections per day, type of needle (length and gauge), needle reuse, injection site rotation, ice-cold insulin injections [6], distance between injection sites (centimeters), intra-LH injections, rate of unexplained hypoglycemia (hypo), blood glucose variability (GV)