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Adding a stimulant's appetite-suppressing effects on top of age-related malabsorption creates a compounding risk

While microbes and their products can breach the intestinal epithelium during normal cellular processes including luminal antigen sampling, dead cell extrusion, or programmed cell death, their systemic spread is restricted by specialised immune cells residing within the underlying lamina propria (Smith et al

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For peptides targeting gut-related aspects of lupus, oral delivery may offer advantages by directly contacting the intestinal mucosa

Some patients experienced mild crusting