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The second mechanism by which glutathione causes lightening of skin is inhibition of transfer of tyrosinase to premelanosomes for melanin synthesis.[] The third mechanism of tyrosinase inhibition is through its antioxidant effect as it scavenges the free radicals generated in the epidermis following UV light irradiation

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Although ELAVL1 expression level is at the highest in the basal subtype, this is the subtype where we measured the lowest KGA/GAC mRNA ratio

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