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Leukemia 35:35263533 Trakada G, Kastritis E, Gavriatopoulou M, Velentza L, Fotiou D, Ziogas DC et al (2019) Pulmonary function abnormalities are common in patients with multiple myeloma and are independently associated with worse outcome

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Directly determining the binding affinities of inhibitors using isothermal titration calorimetry and surface plasmon resonance is too costly

Additionally, the molecule is particularly well conserved within the Caucasoid population, exhibiting limited genetic polymorphisms

PMID: 15 OverdijkMBJansenJHMNederendMLammerts Van BuerenJJGroenRWJParrenPWHIet al