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In conclusion, ERS aggravates the progression of atherosclerosis, while TMAO can selectively bind to the PERK receptor

Current treatments primarily focus on symptom management, but issues such as drug resistance, side effects, and adverse reactions hinder the long-term effectiveness of these therapies

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Recently, ferroptosis has gained attention as a crucial regulatory mechanism underlying the initiation and development of a variety of cardiovascular diseases, including myocardial ischemia/reperfusion injury, cardiomyopathy, arrhythmia, chemotherapy, and Corona Virus-2-induced cardiac injury

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