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Enzymatic lipid peroxidation involves key enzymes such as lipoxygenases, cytochrome P450 oxidoreductase, and cytochrome b5 oxidoreductase

114 Similar effects are observed in liver cancer, 115 pheochromocytoma 116 and NSCLC, 111 and NNT is likely to be activated by NADPH consumption, such as in IDH-mutant cells