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As we age the skins ability to manufacture collagen and elastin declines at the same time that the ability of our skin to protect existing collagen and elastin in the skin diminishes

For example, there is a mitochondrial matrix thiol system that has an important role in antioxidant protection (Murphy, 2012)

Finally, the blood concentration of GSH remains completely stable despite the large transient amino acid input fluctuations

Since these pathogen proteins and metabolites are often similarly structured to ones created by the human host, such molecular mimicry makes it difficult for the host to recognise the foreign pathogen (193), resulting in the hosts immune system becoming increasingly sluggish and more susceptible to acquiring other infectious agents

and strengthens immunity