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2023), stopping the GPx enzymatic reaction as the primary substrate, as shown in Scheme 1

On the other hand, GSH exerts a negative feedback inhibition on GCL

JAMA 321(2):165174 Burt RK, Balabanov R, Han X, Sharrack B, Morgan A, Quigley K, Yaung K, Helenowski IB, Jovanovic B, Spahovic D, Arnautovic I, Lee DC, Benefield BC, Futterer S, Oliveira MC, Burman J (2015) Association of nonmyeloablative hematopoietic stem cell transplantation with neurological disability in patients with relapsing-remitting multiple sclerosis

USA 94 , 1091910924 (1997)

Wang CC, Lee CM (2001) Denitrification with acrylamide in pure culture of bacteria isolated from acrylonitrile-butadiene-styrene resin manufactured for wastewater treatment