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The efficient rate of GSH synthesis and high levels of GSH-dependent enzymes are characteristic features of healthy skeletal muscle where, besides the canonical functions, it is also involved in muscle contraction regulation

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NAD+ production creates a byproduct called homocysteine that requires methyl groups to process safely

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Nucleic Acids Res 15(13):54435459 Colegrave M, Peckham M (2014) Structural implications of -cardiac myosin heavy chain mutations in human disease