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Description

A meta-analysis of randomized controlled trials (RCTs) is summarized, as is an important RCT that was published after the meta-analysis

While supportive evidence has been obtained from animal models and preliminary clinical studies, further large-scale, long-term randomized controlled trials are imperative to establish its safety and evaluate its clinical efficacy comprehensively

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GSTO1 knockdown in HCT116 cells was confirmed by in-gel fluorescence using CMFDA (500 nM) 48 and 72 h post transfection

Firstly, while the role of enhanced glycolysis in fibroblast activation is well-documented, the precise regulatory mechanisms governing this metabolic shift require further investigation