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However, secondary preventative interventions such as antiplatelet drugs, -blockers, angiotensin-converting-enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), and HMG-CoA reductase inhibitors (statins) have been shown to significantly reduce CVD risk [3]

From a PPPM perspective, creatine profiling through biofluids, tissue sampling, and advanced imaging (e.g., proton magnetic resonance spectroscopy) offers a minimally invasive approach for early detection, patient stratification, and monitoring of mitochondrial function

Proline isomerization of histone H3 regulates lysine methylation and gene expression