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27,28 On the other hand, in a recent in vitro study conducted by Binch and colleagues, 29 ADSCs cultured in an IDD-mimicking media (5% O 2 and preconditioning with a proinflammatory stimulus) showed significantly higher levels of pain-associated neurotrophic and angiogenic factors in ADSC cultures compared to BM-MSCs, which may in turn promote neurovascular invasion of the degenerated IVD and thus contribute to discogenic LBP

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doi: 10.1016/j.bbamcr.2019.118535

doi: 10.3390/jfb11030067 Summary Keywords wound healing, pro-inflammatory, diabetes mellitus, cytokines, therapeutic approach Citation Nirenjen S, Narayanan J, Tamilanban T, Subramaniyan V, Chitra V, Fuloria NK, Wong LS, Ramachawolran G, Sekar M, Gupta G, Fuloria S, Chinni S and Selvaraj S (2023) Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

According to medical authorities, neither medication has any proven effect on alleviating COVID symptoms